Yes and no.
As for the EGR side of things, if you are only looking at owning the vehicle for 150,000kms and then selling it, just buy it, drive it and enjoy. If you are looking longer term, you would need to think about modifying the EGR system to prevent the intake manifold clogging up. Either a retune to delete the EGR or a blanking plate or a catch can or a combination. All diesel engines will be the same due to current anti-pollution requirements.
All new fourbies have suspensions designed and tuned for comfort, because that is what the vast majority of consumers want. If you want a suspension to handle endless kms of corrugations and/or to tow a van or camper, you will need to spend money on the suspension at some stage. If you are sticking to the black top and an occasional NP, just buy it and drive it.
As for the Isuzus, they have a strong, reliable and proven engine coupled to a strong, reliable auto box and tow very well. Stick it in D for drive and enjoy.
Good luck with your decisions.
KB