Plus one for Sophos..
As a sys admin I have looked after a large install (3000 odd users) and a small one (25 users) both with Sophos and never had a drama.
For domestic use I always recommend Avira because they have a free version (
www.feee-av.com) but I have also deployed that for small businesses in the past (not the free version, the business version) and had good results.
I guess the thing to remember is not only is there a different between home and business, there is also a difference in small business, medium business and enterprise. All have different needs and really different products that fit.
JMHO but:
Home - Avira free (or upgrade if you don't like ads when updating
Small businesses - Avira business (might be called something different)
Medium - Sophos sbe
Enterprise - full blown Sophos