No AV is infallible....however, (roughly) 10yr's ago, I done a test using some of the more popular AV's at the time - eg: Norton's, Trend, Avast, that free one that use to be quite popular - I forget what it was called, Nod32.
Was done on the same clean installed machine for each test. Had a contact create and send me a virus so I wouldn't know it's 'make up', and tested the AV's against it.
I was surprised at the failure of most of them, but long story short....Nod32 won hands down, and I've had a multi machine license ever since. Yeah, 10yr's is a long time in the puter world, but 2 of them license's are on our now late to mid 20's sons, who use their machines with no care in the world what links they click on
so my vote will always be with Nod....that is until such time I've found it's let me down. I also restore a known clean image monthly onto our machine(s)
I've always run the Microsoft free antivirus and security software which they don't advertise that much I can't justify paying for anti virus software from companies who are responsible for developing most of the virus's etc. Now I run macs don't rally have to worry though.
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Nothing whatsoever to do with it's OS though, is it?....only supply and demand, same as there's more parts out there for commonwhores, than there is for passat's