If you go and not take the kids to Disneyland they will never,ever forgive you
For what it's worth, and I have done exactly what you're thinking about, we stayed at the "Tropicana" motel in Annaheim, twice
they have a breakfast of sorts, nothing flash , but it means you're not going to look for something to eat as soon as you get in the gate at DW, it's also within easy walking distance, another +, also check if the kids stay in the same room as you they may stay for free. Allow 3 days to do all the rides etc, you might do them in 2, if so go back and do your favorites again
Similar to be said for Universal Studio's, try and work out what you want to see and get a timetable before you go as a lot of the show times overlap. Bus travel time Annaheim to U/S was about 1.5 hours each way
You can do a day trip to Sandiego , it's only about an hour and a half by bus from Annaheim or stay overnight, but if you have been to Seaworld in Qld it's very similar, if you do go spend the extra and do the behind the scenes tour as well.
These are things the little kids and the big kids will both enjoy ( Disneyland aint just for little kids
)
1 of the cheaper ways to go is to get a "package" that includes D/L tickets/flights/accommodation and extend your stay for as many days as you want.
Trick. organise your transfers before you go, may not be any cheaper but it's 1 less thing to worry about when you're jet lagged and the kids are ratty at 10am.(it's a 14 hour flight )
Trick. take lots of US $1-00 notes for tipping ( at least $20-00 for the 1st 2 days)
Trick. take 1 suit case inside another, kids clothing and sneakers are VERY cheap
Trick. If there is no breakfast where you stay, find a supermarket and buy a cheap toaster ( $7 to $10 ) bread, butter, spreads, paper plates and plastic knives etc this will save you a fortune ( just don't burn the toast or the smoke alarms will go off
)
San Fransisco is a beautiful place and very interesting, for adults, not so much for little kids, Bronny and I loved it .
Enjoy planning the trip, it's half the fun
ps I think in September D/L doesn't open until about 10am and closes early but check anyway