Driven that road heaps of times. Sealed the full length (any newish roadworks not withstanding). Ever reducing stretches between the Towers and Lynd Junction are a single lane wide, and unless the mine's shut down, triple road-trains travel both directions, and transmit a warning at designated "Call Points", so that if you're listening to UHF40, you'll have an idea that they're approaching.
The Lynd Pub is off to your left a km or so, at the Lynd Junction. It's worth a quick detour as it boast (or used to last time I was there) the shortest bar in Australia. About a 6 hour trip Towers to Kuranda as a guide. Plenty of fuel stops if required. If you'd like an interesting detour, take the dirt road (Silver Valley Rd) from just north of Innot Hot Springs to Herberton. It cuts off lots of bitumen km but takes as long as the bitumen.